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Atlas to Parthenon Migration Guide

This guide helps informatics teams migrate an institution from a running OHDSI Atlas + WebAPI installation to Parthenon. The process is designed to be low-risk and fully reversible: you can run both systems in parallel until validation is complete, then cut over at a scheduled time.

What Transfers Automatically

ArtefactHow it migrates
Cohort definitionsCLI import or UI bulk upload from Atlas JSON exports
Concept setsCLI import or UI bulk upload from Atlas JSON exports
Data source connectionsCLI import from live WebAPI instance
VocabularyShared --- Parthenon connects to the same CDM/vocab schema as Atlas
Achilles resultsShared --- Parthenon reads the same results schema

What Requires Manual Work

ArtefactNotes
User accountsMust be recreated in Parthenon (bulk CSV import supported)
Analysis results (IR, characterization)Re-run analyses after import
Atlas bookmarks / saved searchesNot migrated; document and recreate in Parthenon
Custom Atlas plugins / visualisationsEvaluate Parthenon equivalent features

New Capabilities After Migration

After migrating to Parthenon, your team gains access to capabilities that have no Atlas equivalent:

  • Genomics --- VCF upload, ClinVar annotation, variant browsing, tumor board, genomic cohort criteria
  • Imaging --- DICOM study browser, built-in Cornerstone3D viewer, imaging cohort criteria, population analytics
  • HEOR --- Cost-effectiveness analysis, budget impact modeling, care gap identification, payer contract simulation
  • FHIR EHR Integration --- Connect to Epic, Cerner, and other FHIR R4 servers for automated data sync
  • AI-Powered Search --- Natural language concept search, contextual help, clinical text summarization
  • Expanded Analyses --- SCCS, Evidence Synthesis, PLE and PLP configuration UIs with R/HADES execution

See Chapter 6 --- Feature Comparison for the complete feature-by-feature mapping.

Estimated Timeline

ActivityTypical duration
Parthenon instance setup1--2 days (use the Python installer)
Atlas export1--4 hours
Import and validation1--2 days
User onboarding1 week (staggered)
Parallel operation period2--4 weeks
Atlas decommission1 day

Prerequisites

Before starting migration:

  1. Parthenon is running and accessible at its production URL.
  2. CDM source is connected --- at least one Source with CDM, Vocabulary, and Results daimons configured.
  3. Atlas is accessible --- you have admin access to the Atlas instance and know its WebAPI URL.
  4. PHP CLI access --- you can run php artisan commands inside the Parthenon container or on the host.

See Chapter 1 --- Before You Begin for the full prerequisite checklist.